Acta Derm.Venereol. Mucosal tissue, moles, birthmarks, large/extensive genital warts, bleeding warts. Podophyllum is a plant. View abstract. To … 5-Fluorouracil in the treatment of penile and urethral condyloma acuminata. ... Podophyllotoxin, a chemical found in podophyllum, is safer and has largely replaced podophyllum as a treatment. The differences in side effects between treatment groups were statistically not significant (P=0.24). Only to be applied by doctor. Wallin, J. How Polyphyllin Wart Treatment Works. An effective wart treatment for genital warts is the use of Polyphyllin resin. Use podophyllum only as directed. Br J Vener Dis … The root and underground stem (rhizome) are used to make medicine. This treatment, provided in the doctor's office, has a fairly high success rate at removing active warts on the genitalia and has minimal side effects. Conclusions: The current study, a direct comparison of both, confirms the previously obtained mathematical data, that imiquimod 5% cream and podophyllotoxin 0.5% solution have an identical beneficial effect on anogenital … A comparative study. Avoid EtOH for several hours after treatment. This questions the entire concept of weekly applications of podophyllin for the treatment of genital warts. Avoid in patients with diabetes or circulatory problems. Find everything you need to know about Podophyllum Resin (Podocon-25), including what it is used for, warnings, reviews, side effects, and interactions. Breast feeding. Wart Treatment: Podophyllin. Cantharidin-Sal Ac-Podophyllin Solution Side Effects by Likelihood and Severity COMMON side effects. Further, alternative regimens might be associated with more side effects. 1978;58(2):163-168. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. von Krogh, G. Topical treatment of penile condylomata acuminata with podophyllin, podophyllotoxin and colchicine. After you apply them to an external wart, let the area air dry before you put on clothing. Podophyllum is likely unsafe when taken by mouth or applied to the … Podophyllin: Uses & Side Effects. Cautions. Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack and any additional information you are given by your doctor. To do so may increase the chance of too much medicine being absorbed into the body and the chance of side effects. When podophyllin resin is used to treat genital warts, the skin should be washed one to four hours after application to reduce local irritation. Less data are available regarding the efficacy of alternative regimens for treating anogenital warts, which include podophyllin resin, intralesional interferon, photodynamic therapy, and topical cidofovir. Limit application to small area of intact skin. 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